Background: Given the unprecedented number of traumatized refugee minors in Europe and the increased prevalence of mental disorders such as PTSD Parts in this vulnerable population, new methodologies that help us to better understand their symptomatology are crucial.Network analysis might help clinicians to both understand which symptoms might trig

Proteus mirabilis often complicates the care of catheterized patients through the formation of crystalline biofilms which block urine flow.Bacteriophage therapy has been highlighted as a promising approach to control this problem, but relatively few phages infecting P.mirabilis have been characterized.Here we characterize five phages capable of inf

The Deleted in Colorectal Carcinoma (Dcc) receptor plays a critical role in optic nerve development.Whilst Dcc is expressed postnatally in the eye, its function remains unknown as Dcc knockouts die at birth.To circumvent this drawback, we generated an eye-specific Dcc mutant.To study the organization of the retina and visual projections in these mi

Substantial clinical evidence supports the notion that ciliary function in the airways is important in COVID-19 pathogenesis.Although ciliary damage has been observed in both in vitro VOLUME INJECTION SHAMPOO and in vivo models, the extent or nature of impairment of mucociliary transport (MCT) in in vivo models remains unknown.We hypothesize that S

Abstract Bis(monoacylglycero)phosphate (BMP) is a major phospholipid constituent of intralumenal membranes in late endosomes/lysosomes, where it regulates the degradation and sorting of lipid cargo.Recent observations suggest that the Batten disease-associated protein Twin Sleigh Bed w/Storage CLN5 functions as lysosomal BMP synthase.Here, we show